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8 , 9 , 10 , 11 , 15 In brief, STEP 1, 3 and 4 enrolled adults aged 18 years with a BMI 27 kg/m 2 (with 1 weightrelated comorbidity) or 30 kg/m 2 , without diabetes

If you frequently forget doses, discuss alternative medication delivery methodssuch as oral semaglutide or oral tirzepatidewith your healthcare provider

Tirzepatide is available under FDA-approved prescription uses, while retatrutide is still investigational

It focuses on dose logs, tracking analytics, and side-effect profiling

doi: 10.1056/NEJMoa2107519 26 LudvikBGiorginoFJodarEFriasJPFernandez LandoLBrownKet al
