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Weight-loss Generic Drugs: Biocon plans to file for regulatory approval of its weight-loss generic Semaglutide in Canada this quarter, aiming for a market launch by early 2027

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Ozempic has become popular for weight loss, but brand-name costs, gastric side effects, and supply constraints affect many patients

The exendin-4-induced suppression was mimicked by perfusion with 8-Br-cAMP (a cAMP analog), but was eliminated by the protein kinase A (PKA) inhibitor Rp-cAMP/KT-5720

Its pathogenesis is unknown