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Description

For people with diabetes who are taking insulin or sulfonylureas, Saxenda may increase the risk of hypoglycaemia, and dose adjustments of these medications may be necessary

However, heterogeneity was considerably reduced vs placebo in a sensitivity analysis excluding one trial with short duration and one trial in which all participants were on background insulin therapy

P4HA1: prolyl 4-hydroxylase subunit alpha-1

Appetite remains reduced but you're learning what portions work for your new normal

GLP-1 medications typically produce: Lower postprandial glucose peaks (post-meal spikes become flatter and shorter) Reduced fasting glucose over time as weight decreases Improved Time in Range (TIR) the percentage of time your glucose stays between 70180 mg/dL, which is the key CGM metric for diabetes management Because the oral pill is taken daily rather than weekly, the GLP-1 effect on gastric emptying may be more consistent throughout the week though individual CGM patterns will vary