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The postsynaptic neuromuscular dysfunction in MG is produced by IgG autoantibodies which act by three main mechanisms: (1) direct functional blockade of the receptors, (2) antigenic modulation leading to receptor internalisation and degradation and (3) complement activation and destruction of the membrane [6]

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The peptide sequence contains an Aib residue at position 2, which occupies the DPP-4 binding site, conferring DPP-4 resistance

Though the majority of Lyme disease patients improve after a round of antibiotics, about 10 to 20 percent of treated patients may have lingering symptoms of fatigue, musculoskeletal pains, disrupted sleep, and lack of customary mental functions, Melia and Auwaerter wrote

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