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doi: 10.1053/j.gastro.2004.04.063

The guidelines warn, however, that GLP-1 receptor agonist therapy is not indicated for all patients and should be used with caution in patients with a history of significant gastrointestinal disease, such as a diagnosis of gastroparesis, due to a possible exacerbation of the condition with incretin mimetic therapy

Methods A comprehensive search identified relevant randomized controlled trials comparing combination therapy with SGLT-2i and GLP-1RA to monotherapy or treatment as usual (TAU)

Botana M, Escalada J, Merchante , Reyes R, Rozas P (2022) Prevention of cardiorenal complications with sodiumglucose cotransporter type 2 inhibitors: a narrative review

The drugs reach manyfold higher levels of GLP-1 than any food, Dariush Mozaffarian, a professor at Tufts Friedman School of Nutrition Science and Policy, told me

Shes able to delete diagnoses off their charts, often showing patients just how much they improved over a year, letting them view lab results side by side, where they can see improvements in liver function, cholesterol values, and blood sugar