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Also, obesity is associated with shorter longevity and a significantly increased risk of CVD morbidity and mortality compared with normal body mass index (BMI) [67-69]

Based on the existing evidence, these ongoing trials are expected to further expand our understanding of the cardiovascular effects of tirzepatide, providing stronger support for its use in the integrated management of patients with type 2 diabetes and cardiovascular disease

For Ozempic, which is FDA-approved for type 2 diabetes, the dosing schedule starts at 0.25 mg and escalates, with options to increase to 0.5 mg at week five, then 1.0 mg, and potentially up to 2.0 mg

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The reduction occurred even in sedentary participants, suggesting that HMB has potential that extends far beyond standard muscle-building supplements

They might, particularly for women with PCOS or obesity-related hormonal imbalances