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Multi-country, multi-center long-term cardiovascular outcome trials (CVOTs) confirmed that GLP-1RAs decrease cardiovascular mortality and provide cardiovascular benefits to reduce the incidence of MI or non-fatal stroke [3]

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Clinical trials The US Food and Drug Administration (FDA) has received more than one thousand reports of adverse mental health side effects related to the class of drugs known as GLP-1 agonists to the FDA Adverse Event Reporting System (FAERS)