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However, these drugs have been designed to treat type 2 diabetes, not CNS diseases [203,204,205]

In the United Kingdom, diabetic neuropathy affects a substantial proportion of people with type 2 diabetes, with prevalence increasing with disease duration and suboptimal glycaemic control

9 Fanjiacun Road, Fengtai District, Beijing 100070, China More Information Corresponding authors: [email protected] (L.Y.)

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Several medications have been tried for the treatment of NAFLD/NASH, especially medications that ameliorate the metabolic profile of the patients, insulin sensitivity and lipid oxidation, thus decreasing the lipid burden and improving steatosis and inflammation