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Retatrutide is an investigational peptide currently being studied for its interaction with three key metabolic receptor pathways: GLP-1 (glucagon-like peptide-1), GIP (glucose-dependent insulinotropic polypeptide), and glucagon receptors

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N Engl J Med 381(7):637646 Tornehave D, Kristensen P, Rmer J, Knudsen LB, Heller RS (2008) Expression of the GLP-1 receptor in mouse, rat, and human pancreas

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Mechanisms of amylin/leptin synergy in rodent models

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