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Future research endeavors should prioritize identifying the variables responsible for heterogeneity in meta-regression analyses, including factors such as gender, drug dosage, and study duration, which can impact changes in HbA1c and weight

This variation within the included studies limits the generalizability and validity of the pooled estimates

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In the SURMOUNT-1 trial, participants taking the highest dose of Mounjaro (15 mg) lost an average of 22.5% of their total body weight over 72 weeks, with 57% of participants achieving 20% or greater weight reduction

It works by reducing appetite and increasing feelings of fullness
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