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For weight management, guidelines recommend reassessment approximately 12 weeks after reaching a maintenance dose to determine whether to continue therapy, though weight loss may continue beyond this timeframe in some patients

They increase sodium excretion through the kidneys, which pulls water along with it

Impact of BMI and comorbidities on efficacy of once-weekly semaglutide: Post hoc analyses of the STEP 1 randomized trial

Real-world dosing often deviates from these clean escalation charts, and understanding those deviations helps set realistic expectations

In this case, do not use it

Patients should only follow dosing schedules prescribed by their healthcare provider