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Though the site of action of GLP-1 agonists is an area of ongoing study (see section 6.1), knockdown and knockout studies of GLP-1 Receptors (GLP-1R) reveal that the glucose-controlling effects of GLP-1 are reliant on GLP-1R expression in peripheral neurons (Varin et al., 2019

Body weight plays a role in this variation, though it is not the only factor

Longer-acting versions that require less frequent dosing are another area of research

Similar to Zepbound, the dose is typically increased every four weeks

As a result, ongoing research and clinical trials are essential to establish clear guidelines and recommendations for the safe use of Mounjaro in pregnant populations, ensuring that both maternal and fetal health are prioritized

Common Side Effects and What to Expect GLP-1 medications can cause side effects, with gastrointestinal effects being the most common