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Cohorts who were unresponsive to previous strategies like portion control may be responding to the new GLP 1 drugs.

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Individuals achieving 5% weight loss from baseline body weight had significantly lower AF incidence (OR 0.83, 95% CI 0.780.89), whereas no significant differences were observed in those with no weight loss or weight gain (OR 1.05, 95% CI 0.971.12)

Semaglutide reduces appetite significantly, but calorie intake still matters for sustainable weight loss
