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GLP-1 Agonists Show Promise in Treating Substance Use Disorders Nov 7, 2025 5 min read Updated: Dec 17, 2025 In recent years, medications originally developed to treat Type 2 diabetes, obesity, and other weight-related conditionssuch as semaglutide and liraglutideare showing promise in treating substance use disorders (SUDs)

Impact of treatment with saxagliptin on glycaemic stability and beta-cell function in the SAVOR-TIMI 53 study

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1,2 More importantly, they reduce life expectancy by 814 years on average, 2,3 often due to cardiometabolic comorbidities

If HbA1c doesn't improve after 3 months on medication, dosing or approach may need adjustment