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One could argue that, given the available evidence, an agnostic wait and see position on tamoxifen DDI is ethically untenable, and that many women with breast cancer are currently being subjected to an unnecessary risk of cancer recurrence

Adoption survives side effects, cost, counselling, follow-up, habit, fear and reality

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Starting a GLP-1 without addressing hormonal optimization is leaving a major piece of the puzzle on the table for most active patients.