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FDA-labeled warnings include: Risk of thyroid C-cell tumors (contraindicated in patients with personal/family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2) Pancreatitis (report severe abdominal pain, with or without vomiting) Gallbladder disease (including gallstones and cholecystitis) Acute kidney injury secondary to dehydration from gastrointestinal symptoms Hypoglycemia when used with insulin or insulin secretagogues (dose adjustments may be needed) Diabetic retinopathy complications in patients with type 2 diabetes and pre-existing retinopathy Suicidal behavior and ideation (monitor for depression or suicidal thoughts) Intestinal obstruction/ileus (particularly with severe constipation) These medications are contraindicated during pregnancy and should be discontinued at least two months before a planned pregnancy

147 The risk of aspiration, due to retained gastric contents, is also a concern when performing upper gastrointestinal endoscopy

The most common time to see side effects like these are when you initially start the medication or when you are increasing the dose

Evaluate various types of joyful movement that you can implement into your daily routine as a lifelong commitment

That concomitant gut-dysbiosis (microbial imbalance alongside another condition that drives chronic inflammation) being addressed in the gut then helps reduce overall inflammation

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