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The constipation mechanism is fundamentally the same across all of them, though the severity can vary based on dose, individual biology, and which specific side effect profile you experience

This has led to pharmacies and companies selling their own versions of this medication

For others, particularly during the initial weeks of treatment, the slower transit time can lead to a temporary increase in feelings of fullness and bloating

glucose-dependent insulin secretion Benefits: glycemic control + weight loss + cardiovascular protection Main adverse effect: GI upset

And theres really three separate but related dimensions to reward

Implication: research supports coaching for weight loss adherence