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In the trial-product estimand analysis (accounting for treatment adherence), reductions reached 22.7% and 2.3%, respectively, corresponding to an absolute weight loss of -21.6 kg with combination therapy
The provision of CGM throughout the study and comprehensive diabetes education, including carbohydrate counting and individualised insulin adjustment, probably enhanced participants understanding of their diabetes management and contributed to improved treatment satisfaction and confidence in glycaemic management even in the usual care arm

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Review your diabetes management plan if glycaemic control is suboptimal

Research has examined how dual GLP-1/GIP receptor activation may produce complementary effects on glucose homeostasis, appetite regulation, and energy metabolism

Additionally, if symptoms include features not explained by Wegovysuch as significant respiratory distress, chest pain, or confusionseek medical assessment promptly