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But like any powerful tool, how you use it makes all the difference

PEGylated GLP-1 analogs have been investigated by several groups

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Monitoring may be appropriate

An important nuance: while the trials did not publish detailed BMI-stratified results in their primary papers, the data consistently shows that higher baseline BMI correlates with greater absolute weight loss in kilograms, while lower baseline BMI correlates with greater percentage weight loss

This is why experts increasingly emphasize prevention rather than waiting for complications to appear