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Efficacy and safety of LixiLan, a titratable fixed-ratio combination of insulin glargine plus lixisenatide in type 2 diabetes inadequately controlled on basal insulin and metformin: the LixiLan-L randomized trial

(2012) demonstrated that genetic overexpression of GIP in mice resulted in a favorable lowering of pro-inflammatory gene expression in adipocytes, as well as resistance to diet-induced obesity and improvements in glucose homeostasis

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