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The analysis also identified additional symptoms that may warrant further investigation, including reproductive issues such as irregular menstrual cycles and temperature-related complaints such as chills and hot flashes

And spoiler alert: Theyre really not into this trend

doi: 10.1177/1479164111404257 [DOI] [PubMed] [Google Scholar] 7

112 Decreased BBB permeability and upregulated expression of tight junction proteins were observed in germ-free adult mice

TRT may also slightly improve baseline metabolic rate, which can enhance the weight loss response to GLP-1 agents by 510% in some studies, though individual variation is substantial