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NICE guidance suggests that couples should be offered fertility assessment if they have not conceived after 12 months of regular unprotected intercourse, or after 6 months if the woman is 36 years or over, or earlier if there are known fertility concerns

[DOI] [PubMed] [Google Scholar] Wang Q, Li L, Xu E, Wong V, Rhodes C, Brubaker PL

Obesity is linked to over 200 related diseases including type 2 diabetes, heart disease, and at least 13 types of cancers

They work in ways that can affect appetite, food intake, blood sugar, and stomach emptying

"The glucagon-like peptide 1 analogue Exendin-4 attenuates the nicotine-induced locomotor stimulation, accumbal dopamine release, conditioned place preference as well as the expression of locomotor sensitization in mice." PloS one 8.10 (2013): e77284