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Description
It is a reason to escalate more slowly, to take GI management seriously from day one, and to understand that a rough week does not mean the drug is not working or is not right for you

Then came the larger trial

Adverse reactions to drugs Medicines guidance BNF

Those with baseline gastrointestinal sensitivity, diabetes requiring insulin, liver disease, or a history of alcohol use disorder face higher risks

The Short Answer: Sometimes

The key is coordinating dosing schedules and monitoring how your body responds to both treatments over time
