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Schroder, J

TRIUMPH-4: Osteoarthritis pain signal Because TRIUMPH-4 specifically enrolled participants with symptomatic knee osteoarthritis, it also collected WOMAC (Western Ontario and McMaster Universities Osteoarthritis Index) pain data

Safety: GI events remain the class effect
Upper abdominal pain, nausea, and fever should be reported to your healthcare provider

Similarly, people with a history of psychiatric medications were 12% more likely to discontinue treatment within the first year, while those living with cardiovascular disease or other chronic conditions were around 10% more likely to stop treatment early -- also suggesting a higher likelihood of experiencing adverse effects

Depending on clinical findings, further investigations such as upper gastrointestinal endoscopy (gastroscopy) may be indicated to visualise the oesophagus, stomach, and duodenum directly
