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Manufacturers with experience developing the COVID-19 vaccine will have the infrastructure and technical know-how to produce safe and effective mRNA drugs for clinical and commercial use. The inherent complexity of modern therapies necessitates a robust and adaptive fillfinish capability that can handle everything from high-volume production runs to the meticulous requirements of advanced, individualized treatments

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5 The patient was premedicated with midazolam 2 mg iv and preoxygenated with 100% oxygen for three minutes

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