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Weight loss typically begins in the first 24 weeks as appetite suppression kicks in, with cumulative reductions accelerating through months 36

Each injection session is quick and easy, typically administered at a healthcare facility, though some patients may be trained to self-administer the injection at home after their first few sessions

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The majority of TH-positive neurons expressed GLP-1R, but in the AP only a limited number of PrRP-positive neurons also expressed TH, suggesting activation of different cell populations expressing the GLP-1R in AP