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Due to their preclinical testing and lack of comparison with other dual receptor agonists such as tirzepatide, further studies are needed to determine whether the effects of these unimolecular compounds are superior to those of clinically tested drugs

Concurrent ICV administration of GLP- 1 and GIP significantly increased neuronal activation and pro-opiomelanocortin expression in the arcuate nucleus of the hypothalamus

These two mechanisms collectively reduce cravings, slow down digestion, and effectively improve blood sugar controlkey components for successful weight management

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