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Diabetes leads to a significantly accelerated incidence of various related macrovascular complications, including peripheral vascular disease and cardiovascular disease (the most common cause of mortality in diabetes), as well as microvascular complications such as kidney disease and retinopathy

Across the research so far: ~54% fewer alcohol-related events ~45% lower relapse 3050% lower odds of developing AUD

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GIPR antagonist AMG-133 12 16% weight loss ,

GLP-1 medications begin reducing appetite within days, but meaningful weight loss typically emerges over weeks and months