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37 Similarly, in a retrospective cohort study of 3435 people with type 2 diabetes exposed to tirzepatide for 180 days and over compared with a matched unexposed cohort, tirzepatide was associated with an increased risk of new-onset proliferative diabetic retinopathy primarily in those with pre-existing nonproliferative diabetic retinopathy

The drug has also shown significant improvements in blood sugar, lipids, and other metabolic parameters, making it a strong candidate for treating complex, multi-factor obesity

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Trade tensions between the US and China are adding to the interest in Indian contract manufacturing players for steady supplies

doi: 10.1016/j.cell.2016.05.044