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Table 9 provides dosing recommendations in the presence and absence of renal impairment

As frequently recognised co-morbidities with atherosclerotic cardiovascular disease (ASCVD), type 2 diabetes mellitus (T2DM) and overweight/obesity are rapidly becoming pandemics of dysregulated metabolic health

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However, this is unlikely, as Ex4 reduces intravenous self-administration of alcohol in male mice (Sorensen et al., 2016) and the GLP-1R agonist does not reduce water intake
