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Drinking alcohol while taking GLP-1 medications should be done with caution
Some patients see improvement in psoriasis even before significant weight loss, suggesting a direct anti-inflammatory effect

Cardiovascular disease

Niacinamide combinations represent another approach to optimizing results without switching the base medication

The SURMOUNT-4 trial with tirzepatide showed that participants who continued the medication lost an additional 5.5% of their body weight, while those who switched to a placebo regained 14%

Therefore, we speculated that T cells could induce microglial polarization through direct contact, cytokine-mediated communication or antigen presentation, thereby amplifying their impact on the cerebral immune milieu
