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However, challenges such as high treatment costs and competition from alternative therapies may impact growth in some regions

Canagliflozin combined with metformin versus metformin monotherapy for endocrine and metabolic profiles in overweight and obese women with polycystic ovary syndrome: A single-center, open-labeled prospective randomized controlled trial

Additionally, within the incretin drug pipeline, retatrutide, a unimolecular peptide with tri-agonist activity at the GIP, GLP-1 and glucagon receptors, recently showed promising results in a phase 2 evaluation for both weight loss and glycaemic control [171]

Understanding this connection is essential for patients considering these therapies, particularly those with existing gallbladder concerns

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While ertugliflozin did not outperform placebo for MACE, it significantly reduced hospitalizations for HF by 30% (59)
