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This strongly suggests that the migraine benefit was independent of weight loss

Semaglutide is not a shortcut for people looking to lose a few vanity pounds

Science 2021;373:1040-6

Researchers dont fully understand this link, but it seems related to a rapid fall in blood sugar

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Changes in Cholesterol and Lipid Panel Results Weight loss from semaglutide therapy triggers shifts in blood lipid profiles that are entirely separate from direct drug effects
