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Med 38(11):602606 Gallwitz B (2019) Clinical Use of DPP-4 Inhibitors

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A 52semanas se observa reduccin del volumen circulante y de la presin arterial, en relacin con la reduccin de adipoquinas y aldosterona, acompaado de disminucin de albuminuria y aumento de filtrado glomerular respecto a placebo, sugiriendo beneficio renal aadido47
These work locally rather than systemically, addressing areas that resist overall weight loss

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GLP-1 receptor agonists and renal outcomes in patients with diabetes mellitus type 2 and diabetic kidney disease: State of the art