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In this study, we first characterized the expression of GLP-1Rs and their distribution throughout the different cell types that make up the wall of collecting lymphatic vessels and surrounding tissues by means of a single-cell RNA sequencing (scRNAseq) dataset recently generated and published by our group 47 and fluorescence confocal microscopy

The action is self-limiting as when the increased insulin release reduces plasma glucose, the ability of GLP-1 to act is turned off (44)

Phase Phase 5 High escalation Weeks Weeks 1720 Dose 12.5 mg once weekly Notes Transitional

Saper, C

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