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Prior to that, the treatment of obesity has been predominantly limited to lifestyle interventions and bariatric surgery
In the Diabetes, Obesity and Metabolism study mentioned above, the authors noted that stopping lifestyle changes may have contributed to the weight regainmeaning, rebound hunger wasnt the singular culprit
This author has long recognized the need for a shift of clinical focus from glycemic status to insulin homeostasis for detecting and optimally managing adverse metabolic, proinflammatory, endothelial, developmental, and neurologic effects of hyperinsulinism (ref
PMCID: PMC8504381
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Hypoaminoacidemia underpins glucagon-mediated energy expenditure and weight loss
