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Metabolic rate decreases beyond what the lost weight alone would predict, a phenomenon called adaptive thermogenesis
He used a medication called Tirzepatide, which mimics the action of GLP-1 plus another hormone called GIP [1]
doi: 10.1136/svn-2018-000196 42 DoughertyJAGuirguisEThornbyKA
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And the solutions are more straightforward than most people realize
2023 Aug;47(8):677-685
