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A few tactics to assist are beginning with lower doses, scheduling check-ins, or implementing reminders

Your healthcare provider may recommend another type of birth control for 4 weeks after you start Mounjaro and for 4 weeks after each increase in your dose of Mounjaro

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Tighten your sleep window and plan simple meals you can repeat

But the general principle applies: the more aggressive the weight loss, the more likely short-term fatigue during adaptation

For some people, the benefits of these medications do not outweigh the risks, as with any other pharmacologic intervention (e.g., adults who have previously had medullary thyroid cancer, in which they are contraindicated)