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Bravo TV host Andy Cohen says he lost a good chunk of weight by microdosing a GLP-1 drug all summer, though he didnt say which one or offer details of his regimen

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Gerstein HC, Hart R, Colhoun HM et al (2020) The effect of dulaglutide on stroke: an exploratory analysis of the REWIND trial

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Orforglipron is a selective and potent partial agonist that biases the activation of GLP-1 receptors towards the G-protein signaling pathway and exhibits a lesser ability to recruit -arrestin

GLP-1s are generally well-tolerated with manageable side effects