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These compounds reduce central neuroinflammation by lowering interleukin (IL)-1, IL-6, and tumor necrosis factor-alpha (TNF-), and limiting oxidative stress ( On the other side, current trends in precision psychiatry aim to classify subpopulations of patients with inflammatory depression, characterized by elevated markers of inflammation, increased glucose and lipid levels, neurovegetative symptoms, anxiety or irritability, and suicidal ideation (Wessa et al., 2026)

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Thus, regarding cases with exposure to GLP1-RA of shorter half-lives, such as liraglutide and exenatide, the exposure window did not encompass the entire first trimester of pregnancy in most cases

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