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Some investigators have proposed that GLP-1RAs improve myocardial insulin sensitivity, enhance glucose oxidation rates, reduce fatty acid oxidation, and thereby optimize myocardial energy metabolism, ultimately improving cardiac function.106 In a randomized controlled trial (RCT) conducted by Mikhail et al,106 semaglutide efficacy was evaluated in 616 patients with obesity-related heart failure and T2DM

doi: 10.1002/brb3.1505 238 PanagakiTGenglerSHolscherC

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A Cigna spokesperson confirmed that it was ending the coverage

These drugs mimic natural gut hormones to slow digestion, reduce appetite, and improve blood sugar control

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