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Sources Baxter, S.M

Preclinical studies have evaluated the therapeutic potential of GLP-1 based polypharmacology for the treatment of obesity and diabetes

Some people experience diarrhea, bloating, and feeling too full, which can worsen when they increase their fiber intake too quickly

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GLP-1 agonists directly bind to and activate GLP-1 receptors on pancreatic cells, while berberine works primarily through AMPK activation and does not directly interact with GLP-1 receptors

J Clin Invest 1993;91:3017.ArticlePubMedPMC 56