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30 , 987996.e6 (2019)

GIP and GLP-1 are secreted at low levels in the fasted or interprandial state, and circulating levels rise briskly following a meal or glucose ingestion [50]

10.2337/db12-1116 [DOI] [PMC free article] [PubMed] [Google Scholar] 26.Gaich, G

Instead, peripherally administered GLP-1 analogs access the brain via circumventricular organsregions bordering the third and fourth ventricles where the barrier is specialized to permit signaling between blood and cerebrospinal fluid

A., & Thompson, L