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47 In addition to its direct effects on gallbladder contraction and sphincter of Oddi relaxation, CCK is involved in molecular and neuronal pathways that regulate both gallbladder function and satiety

According to NICE guidelines (NG28), GLP-1 receptor agonists are typically considered when triple therapy is not effective, not tolerated or contraindicated for type 2 diabetes

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Notably, epidemiological data indicate that Asian populations develop diabetes at a significantly younger age than White populations, exhibiting elevated risks of disease-related complications and mortality, thereby imposing a considerable healthcare burden [117]