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Animal studies have provided some mechanistic insights
Addiction medicine has seen little pharmacologic innovation for decades
[DOI] [PMC free article] [PubMed] [Google Scholar] 45.Habegger K.M., Stemmer K., Cheng C., Muller T.D., Heppner K.M., Ottaway N
While not FDA-sanctioned, such rationing is reported in practice to maintain some therapy continuity in the face of obstacles
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Am J Physiol Endocrinol Metab 2004
