glp 1 drugs and gastroparesis Adverse effects of GLP-1 class drugs. Gastrointestinal issues are Does Ozempic Cause Gastroparesis? [2026

GLP-1 RAs are effective and safe treatments for controlling blood sugar levels and reducing body weight, and evidence from large clinical trials also suggests that GLP-1 RAs may be renoprotective

However, no statistical significance was found as far as liver biopsy-based outcomes were concerned [87]

doi: 10.1038/s41591-025-04106-7

There was a dose-response reduction in liver fat from baseline at 24 weeks with increasing retatrutide doses: -82.4% with 12 mg retatrutide vs

If the patient is dehydrated from hypovolemia, then fluid resuscitation may be indicated along with an antiemetic if nausea/vomiting are present

Ocul Immunol Inflamm