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In a study of older men, restless leg syndrome was associated with a higher mortality rate, even after controlling for a number of other variables.[ref] PLMD is negatively correlated with REM sleep duration and is associated with poorer cognitive function in middle-aged and elderly individuals

The reduced risk was consistent when studying only patients with Type 2 diabetes (RR 0.54) or patients without diabetes (RR 0.52)

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No follow-up protocol

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