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The use of incretin mimetics for people with type 2 diabetes and CKD was also considered not cost-effective, despite evidence from the semaglutide FLOW trial
Exendin-4 has a half-life of only 2.4 h in the blood, while semaglutide has a half-life of 165 h [207]
Sharma A, Srenby A, Wernerson A, et al
Lumbar puncture under fluoroscopy showed an elevated opening pressure of 27 cm of water with a closing pressure of 7 cm of water after draining 20 mL of CSF
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