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10.1016/j.biopha.2026.119057 16 NovikoffA.MullerT

A regulatory letter dated March 20, 2019, stated: In order to prevent the patent from lapsing, the amount listed above must be paid within the one-year period of grace Once a patent has lapsed it cannot be revived. The company did not make the payment, resulting in a permanent loss of patent protection

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