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To put that into context, heres how the trial phases usually work: Phase 1: Tests a brand-new drug in a very small group (20 to 80 people) to make sure its safe and to figure out an appropriate dose

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e , NCI-H716 cells were treated with GPCR antagonists (10 M) or vehicle (DMSO) for 15 min before P9 treatment (50 g ml 1 ), then incubated for an additional 2 h, after which GLP-1 secretion was analyzed (n = 6 per group)

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